投稿者 フーリエ 日時 2000 年 11 月 17 日 20:49:10:
回答先: サルの脳を制御アームに接続 投稿者 フーリエ 日時 2000 年 11 月 17 日 20:34:59:
Nature 408, 361 - 365 (2000)
Real-time prediction of hand trajectory by
ensembles of cortical neurons in primates
JOHAN WESSBERG*, CHRISTOPHER R. STAMBAUGH*, JERALD D. KRALIK*,
PAMELA D. BECK*, MARK LAUBACH*, JOHN K. CHAPIN†, JUNG KIM‡,
S. JAMES BIGGS‡, MANDAYAM A. SRINIVASAN‡ & MIGUEL A. L. NICOLELIS*§
* Department of Neurobiology;
§ Department of Biomedical Engineering;
Department of Psychology-Experimental, Duke University, Durham, North Carolina 27710, USA
† Department of Physiology and Pharmacology, State University of New York Health Science Center, Brooklyn, New
York 11203, USA
‡ Laboratory for Human and Machine Haptics, Department of Mechanical Engineering and Research Laboratory of
Electronics, MIT, Cambridge, Massachusetts 02139, USA
Signals derived from the rat motor cortex can be used for controlling
one-dimensional movements of a robot arm1. It remains unknown, however,
whether real-time processing of cortical signals can be employed to reproduce,
in a robotic device, the kind of complex arm movements used by primates to
reach objects in space. Here we recorded the simultaneous activity of large
populations of neurons, distributed in the premotor, primary motor and
posterior parietal cortical areas, as non-human primates performed two distinct
motor tasks. Accurate real-time predictions of one- and three-dimensional arm
movement trajectories were obtained by applying both linear and nonlinear
algorithms to cortical neuronal ensemble activity recorded from each animal. In
addition, cortically derived signals were successfully used for real-time
control of robotic devices, both locally and through the Internet. These results
suggest that long-term control of complex prosthetic robot arm movements can
be achieved by simple real-time transformations of neuronal population signals
derived from multiple cortical areas in primates.