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(回答先: もうひとつ、４番目の原因を忘れていました。 投稿者 Sun Shine 日時 2007 年 12 月 08 日 10:43:19)
以前、チラリと聞いたことがあると思い、友人に聞いたら、彼の肌が白い原因はやはりこれでした。Vitiligo（肌が白くなる病気）にかかっているということで、彼のファン・クラブのニュースにもこのことが載っています。
日本のおじいさん達の中に見かけるあれと同じようなものでしょうか。
http://www.mjfanclub.net/history/vitiligo.html
n 1993, during his famous interview with talk show host Oprah Winfrey, Michael revealed that the cause of his much talked about change in skin color was due to the skin disorder Vitiligo.
Not much is known to the general public about Vitiligo so MJFC has compiled a few facts about the disorder which you will find below. The info on this page has mainly been compiled from the web site of the National Vitiligo Foundation.
For more information on Vitiligo you can check out the following web sites:
National Vitiligo Foundation
National Institute of Arthritis and Musculoskeletal and Skin Diseases
MEDLINEplus
Vitiligo Support
What Is Vitiligo?
Vitiligo (vit-ill-eye-go) is a pigmentation disorder in which melanocytes (the cells that make pigment) in the skin are destroyed. Patients with Vitiligo develop white spots in the skin that vary in size and location. The disease affects both sexes and all races however; the distinctive patches are most noticeable in people with darker skin tones. Approximately 1 to 2 percent of the world's population (or 40 to 50 million people) has Vitiligo! About 95% of people who have the disease develop it before their 40th birthday.
What Causes It?
The cause of Vitiligo is not known, but doctors and researchers have developed several theories. One theory is that people develop antibodies that destroy the melanocytes in their own bodies. The most credible theory, and the most frequently reported precipitating factor, is a single stressful physical or psychological event such as severe sunburn, surgery, pregnancy, loss of job, bereavement, or some other source of emotional trauma or distress. Some believe that the disease is hereditary however most people with Vitiligo have no family history of the disorder.
The beginning of Vitiligo and the severity of pigment loss differs with each patient. The disorder is usually progressive and for some people the depigmentation spreads slowly, over many years. For others, the spreading occurs rapidly. There is no way to predict how much pigment a patient will loose and illness and stress can result in further pigment loss.
Emotional & Psychological Affects
Because Vitiligo causes such a drastically uneven skin color most patients experience emotional and psychological stress, especially if the Vitiligo develops on visible areas of the body, such as the face, hands, arms, feet, or on the genitals. Many patients often feel embarrassed, ashamed, depressed, or worried about how others will react. Some people with Vitiligo have found that using cosmetics to cover the white patches improves their appearance and helps them to feel better about themselves.
Treatment Options
Unfortunately, there is no known cure for Vitiligo at this time. There are however, two basic treatment options: Repigmentation - to try to restore the normal pigment; and depigmentation - to try to destroy the remaining pigment cells.
For repigmentation, new pigment cells must be produced from already existing ones. The patient is given what's called a psoralen drug and then exposed to ultraviolet light (UV-A). When the drug is activated by the UV-A it increases the availability of color-producing cells at the skin's surface. The patient must take the psoralen drug by mouth about two hours before lying in the sun or under artificial UV-A. A doctor's supervision is required during each step of repigmentation therapy.
People with Vitiligo should always protect their skin against excessive exposure to the sun by wearing protective clothing (such as long sleeves, hats, etc.), staying out of the sun at peak periods except during treatment time, and using sunscreen lotions with a SPF of 15 or higher. Potential damage to the eyes can be prevented by wearing special sunglasses with protective lenses. They should be worn during sunlight exposure and for the remainder of the day after treatment with psoralen drugs.
Depigmentation is warranted when a patient has Vitiligo over more than 50% of the body. A cream containing a drug called monobenzone is used to permanently destroy the pigment cells in unaffected areas of the skin and produce a uniform skin tone. After using the drug, the patient should then avoid direct skin-to-skin contact with other people for at least two hours. Depigmentation is permanent and cannot be reversed. Also, people who undergo this procedure should be advised that it does result in extreme photosensitivity (they will always be abnormally sensitive to the sunlight).
Key Words
Antibodies: protective proteins produced by the body's immune system to fight infectious agents (such as bacteria or viruses) or other "foreign" substances.
Depigmentation: loss of color in the skin, mucous membranes, hair, or retina of the eye.
Melanin: a yellow, brown, or black pigment that determines skin color. Melanin also acts as a sunscreen and protects the skin from ultraviolet light.
Melanocytes: special cells that produce melanin.
Pigment: a coloring matter in the cells and tissues of the body.
Pigmentation: coloring of the skin, hair, mucous membranes, and retina of the eye.
Source: National Vitiligo Foundation
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フォローアップ:- Re: 彼の肌が白い原因はこれだった ウソ捏造工場 2007/12/09 08:23:26
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